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Science Journal

 

New York Science Journal

(N Y Sci J)

ISSN 1554-0200 (print); ISSN 2375-723X (online), doi prefix: 10.7537, Monthly

Volume 12 - Number 12 (Cumulated No. 130); December 25, 2019

Cover (jpg), Cover (pdf), Introduction, Contents, Call for Papers, ny1212

 
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CONTENTS  

No.

Titles / Authors /Abstracts

Full Text

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1

Development and Evaluation of an evaporating cooling system for agricultural products

 

1Ogunlade, Clement A., 1Jaiyeoba, Kehinde F., 2Fadara Taiwo and 1Akinsanya Olanrewaju

 

1Department of Agricultural Engineering, Adeleke University, Ede. Osun State, Nigeria

2Department of Mechanical Engineering, Federal Polytechnic, Ede, Nigeria

Corresponding author: clement2k5@yahoo.com

 

Abstract: Evaporative cooler works on the principle of cooling resulting from evaporation of water from the agricultural product. The cooling achieved by this device also results in high relative humidity of the air in the cooling chamber from which the evaporation takes place relative to ambient air. A proper storage of farm produce is needed in other to extend the shelf life of the farm produce. To have a proper storage there is need in controlling both the temperature and relative humidity of the storage area. The essence of storage is important because not all the harvested farm produce is used immediately after harvest; this minimizes spoilage of farm produce and enhances their life span. The evaporative cooling system reduces the storage temperature and also increases the relative humidity within normal level of storage. The cooling system is an enclosed system and air is allowed to pass only through the pad and also a suction fan centrally located which draws in air through the pad. Water drips into the jute pad at a constant rate through a water distribution system. The materials used are: Suction fan, pad end, water reservoir, pipe network, battery, water pump, spinach, okro and melow leaf. This paper reviews the evaluation of the effect of absorbent materials on an active evaporative cooling system for the storage of fruits and vegetables.

[Ogunlade, Clement A., Jaiyeoba, Kehinde F., Fadara Taiwo and Akinsanya Olanrewaju. Development and Evaluation of an evaporating cooling system for agricultural products. N Y Sci J 2019;12(11):1-6]. ISSN 1554-0200 (print); ISSN 2375-723X (online). http://www.sciencepub.net/newyork. 1. doi:10.7537/marsnys121119.01.

 

Keywords: Development; Evaluation; evaporating cooling system; agricultural; product

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Microneedling with Ginkgo Biloba Solution plus Narrow Band Ultraviolet B Phototherapy in the Treatment of Non-Segmental Vitiligo: Comparative Intra-Individual Placebo Controlled Study

 

Mohamed Kotb Ibrahim, Ibrahim Mohamed Abdelkarim, Mohammed Abdalla Ibrahim Mohamed Azzam

 

Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Al-Azhar University, Egypt

 

Abstract: Introduction: Vitiligo is a common cutaneous disease characterized by depigmented skin patches that may become a source of embracement for affected individuals. One of its popular lines of treatment is narrow band UVB that is widely used. Another line is microneedling that aims to induce a minimal superficial bleeding stimulating the releases of growth factor to start a healing cascade to restore normal structure. Although the etiology of vitiligo is not yet well understood, a biochemical theory was proposed suggesting an oxidative stress within the vitiliginous skin. Ginkgo biloba is plant-based medicine used as antioxidant in many specialties. These antioxidant properties can play an important role in protecting melanocytes from the oxidative stress and thus inhibit the progression of vitiligo. Patients and study design: A randomized clinical trial was performed on 20 vitiligo patients selected from those attending at Outpatient Clinic of Dermatology, Al-Azhar University Hospitals. All participants were subjected to full history taking and complete clinical. Those who had vitiligo that was stable at least in the last month prior to study beginning with ages ranging from 10 to 65 years were selected. For each participant, three similar patches were selected; first patch was exposed to NB-UVB, microneedling and ginkgo biloba solution; second patch was exposed to NB-UVB, microneedling and saline; third patch was exposed to NB-UVB only. All patches were treated for 12 weeks. Assessment of repigmentation was performed through three independent investigators. Results: The current study results revealed a significant increase in vitiligo among females than males. In addition, the positive family history was evident in minority of cases. It also found that the most common type of vitiligo is the widely spread type. The present work found a significant improvement in patches exposed to NB-UVB, microneedling and ginkgo biloba solution compared to NB-UVB and microneedling with saline or NB-UVB only. Furthermore, patients’ satisfaction was significantly high in the first group compared with the two groups. It also revealed no significant difference concerning improvement between patches exposed to NB-UVB and microneedling with saline and patches exposed to NB-UVB only.

[Mohamed Kotb Ibrahim, Ibrahim Mohamed Abdelkarim, Mohammed Abdalla Ibrahim Mohamed Azzam. Microneedling with Ginkgo Biloba Solution plus Narrow Band Ultraviolet B Phototherapy in the Treatment of Non-Segmental Vitiligo: Comparative Intra-Individual Placebo Controlled Study. N Y Sci J 2019;12(12):7-14]. ISSN 1554-0200 (print); ISSN 2375-723X (online). http://www.sciencepub.net/newyork. 2. doi:10.7537/marsnys121219.02.

 

Keywords: Microneedling; Ginkgo Biloba Solution; Narrow Band Ultraviolet; Phototherapy; TreatmentNon-Segmental Vitiligo; Comparative Intra-Individual Placebo Controlled Study

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Fractional Carbon Dioxide Laser alone versus Fractional Carbon Dioxide Laser assisted Topical steroid delivery in Treatment of Post-Burn Scars.

 

Prof. Dr. Amr Mohamed Zaky, Dr. Shady Mahmoud Attia Ibrahim, Mohammed Elesawy Mohammed

 

Dermatology, Venereology and Andrology, Faculty of medicine, Al-Azhar University, Cairo, Egypt

 

Abstract: Objective: The purpose of this study was to evaluate the clinical and histopathological effects of fractional carbon dioxide laser alone versus fractional assisted corticosteroid delivery in treatment of post- burn scars. Design: This was randomized, blinded, clinically split scar Study Setting: The setting for this study was Dermatology Department at Al-Azhar University in Cairo, Egypt. Participants: Thirty patients with mature burn scars were included in the study. Measurements: Twelve fractional carbon dioxide laser sessions followed by application of triamcinolone acetonide suspension on half of the scar then other half treated by fractional CO2 laser alone were done 4 to 6 weeks apart. Outcome Measures: Primary outcome was measured using two scar scales, the Vancouver Scar Scale and the university of north Carolina scar score. Secondary outcomes included evaluation of collagen and elastic fibers using routine hematoxylin and eosin, Masson’s trichrome, and orcein stains. Outcomes were measured one month after the last laser session. Results: Both Vancouver Scar Scale and the university of north Carolina scar score showed significant reduction following treatment (p<0.001). area of the scar treated by fractional carbon dioxide laser followed by application of triamcinolone acetonide suspension improved more than the other area treated by fractional CO2 laser alone but the improvement still not significant (p-value > 0.05). The pattern and arrangement of collagen and elastic fibers showed significant improvement (p<0.001, p=0.001, respectively), together with significant improvement in their amounts (p=0.020, p<0.001, respectively). Histopathological improvement was significant in area of the scar treated by fractional carbon dioxide laser followed by application of triamcinolone acetonide suspension more than the other area treated by fractional CO2 laser alone area ( p<0.001). Conclusion: Fractional CO2 laser assisted topical steroid delivery could be considered as a promising option for burn scar management as it improves the clinical appearance of the scar, which was detected histologically by changing the dermal collagen orientation and thickness making it much similar to normal skin.

[Amr Mohamed Zaky, Shady Mahmoud Attia Ibrahim, Mohammed Elesawy Mohammed. Fractional Carbon Dioxide Laser alone versus Fractional Carbon Dioxide Laser assisted Topical steroid delivery in Treatment of Post-Burn Scars. N Y Sci J 2019;12(12):15-26]. ISSN 1554-0200 (print); ISSN 2375-723X (online). http://www.sciencepub.net/newyork. 3. doi:10.7537/marsnys121219.03.

 

Keywords: Fractional Carbon Dioxide Laser; Topical steroid delivery; Treatment; Post-Burn Scars

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The effect of Nigella sativa gel as an adjunctive therapy in patients with chronic periodontitis: A clinical and histological study

 

Maram Albarrak1, Samah Alaqeel1, Ghada Bassiouny2, Shokria Ghneim3

 

1Graduated student, Collage of dentistry, Qassim University, Saudi

2Associate Professor In periodontology and Oral medicine, Collage of dentistry, Qassim University, Saudi Arabia and faculty of Dentistry, Alexandria University, Egypt

3Professor in Oral pathology, Collage of dentistry, Tanta University, Egypt

maram.albarrak@qudent.org

 

Abstract: Aim: Nigella Sativa gel in the treatment of chronic periodontitis. Background: Periodontitis is a destructive, inflammatory, pathological condition that affects the periodontium. It’s characterized by an extreme host reaction to gram negative tooth related pathogens, which destroys the surrounding tooth supporting tissues. World is increasingly trying to replace the synthetic drugs with the therapeutic effect of the natural herbal products. Nigella sativa is an annual flowering plant that has been used from a long time as a herbal medicine that promote tissue healing and modulate host responses. Purpose: the aim of this study was to evaluate the effect of Nigella Sativa (thymoquinone) gel in the treatment of chronic periodontitis. Methodology: Forty periodontal sites in twenty patients with mild to moderate chronic periodontitis aged between 35 and 45 years were included in this study. Full mouth scaling and root planning (SRP) was provided, then subgingival application of the thymoquinone gel to the experimental sites compared to (SRP) only in control sites. The clinical parameters, bleeding index (BI), gingival index (GI) plaque index were recorded at baseline and after 6 weeks post gel application. The anti-inflammatory effect of the Nigella sativa gel was also evaluated by the histological examination of the gingival biopsy. Results: Significant reduction in mean of (BI), (GI) and (PI) was observed from baseline to 6th week post-gel application. The histological results proved that thymoquinone gel was effective in reduction of the inflammatory cells in experimental sites more than the control sites. Conclusion: Local application of thymoquinone gel in conjunction with SRP showed anti-inflammatory effect both clinically and histologically.

[Maram Albarrak, Samah Alaqeel, Ghada Bassiouny, Shokria Ghneim. The effect of Nigella sativa gel as an adjunctive therapy in patients with chronic periodontitis: A clinical and histological study. N Y Sci J 2019;12(12):27-34]. ISSN 1554-0200 (print); ISSN 2375-723X (online). http://www.sciencepub.net/newyork. 4. doi:10.7537/marsnys121219.04.

 

Key word: Periodontitis- Nigella sativa.

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Modified Sinotomy with Marsuplization versus Excision with Lay Open in Treatment of Pilonidal Sinus Disease

 

Ashraf Farouk Abdeer1, Amr Mohamed Elhefny2, Wadie Boshra Gerges3, John Sobhy Mamlouk Sawires4

 

1.  Professor of General Surgery, Faculty of Medicine, Ain Shams University

2.  Assistant Professor of General Surgery, Faculty of Medicine, Ain Shams University

3.  Lecturer of General Surgery, Faculty of Medicine, Ain Shams University

4.  M.B.B.Ch Kasr Alainy Faculty of Medicine, Cairo University

doctor30100@gmail.com

 

Abstract: Pilonidal sinus disease (PSD) is a common infection of the skin in the gluteal cleft, with a prevalence of 0.7% in the general population. Pilonidal sinus can occur in many different areas of the body but most are found in the sacrococcygeal area, in the natal cleft, approximately 5 cm from the anus. This is a prospective comparative randomized study conducted at Department of General Surgery, Imbaba General Hospital to compare the modified sinotomy with marsupialization versus excision with lay open in treatment of pilonidal sinus disease. Pre-study power analysis revealed that a sample size of 30 patients in each group would be sufficient with 80% power and a P value of 0.05. The perfect approach for the management of PNS should be simple, cause minimal pain, have best chance for success and least recurrence rate with low risk for complications, avoid general anesthesia, require minimal wound care, and ensure minimal inconvenience for the patient with rapid return to normal activity. Number of Patients participated in this study were n=60, 77% of the participants were males aged from 17-52 and 26.3 works as drivers. Operative time in modified sinotomy group ranged from 20-40 minutes and in lay open group ranged from 20-35 min (P-value: 0.07). Presence of hair in the back in the modified sinotomy group in 83.3% while in the lay open group 76.6% (P-value: 0.004). In conclusion, we believe that execution of a minimally invasive surgical technique for PSD can be among the most important methods for treating not only primary PSD but also complicated and recurrent PSD cases.

[Ashraf Farouk Abdeer, Amr Mohamed Elhefny, Wadie Boshra Gerges, John Sobhy Mamlouk Sawires. Modified Sinotomy with Marsuplization versus Excision with Lay Open in Treatment of Pilonidal Sinus Disease. N Y Sci J 2019;12(12):35-40]. ISSN 1554-0200 (print); ISSN 2375-723X (online). http://www.sciencepub.net/newyork. 5. doi:10.7537/marsnys121219.05.

 

Keywords: Sinotomy; Marsuplization; Excision; Lay; Open; Treatment; Pilonidal Sinus Disease

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The Role of Ultrasound in Screening of Dense Breast

 

Prof. Magda Shaaban Yakoot1, Dr. Abdalla Hussein Ahmed1, Dr. Gehan Hassan Gamal2, Hanan Shawky Mohammed Al Sorady1

 

1Radiodiagnosis Department, Faculty of Medicine for Girls, Al-Azhar University, Egypt

2 Radiodiagnosis Department, Faculty of Medicine, October 6 University, Egypt

 

Abstract: Background: Despite recent improvements in mammography equipment and technique, the radiographically dense breast remains difficult to image. The problems in imaging the dense breast account for a large percentage of the cases of mammographically “missed” carcinomas. Other imaging modalities-such as ultrasonography, transillumination, thermography, computed tomography, magnetic resonance imaging, and radionuclide imaging-have been investigated for use in breast cancer detection. Objectives: The aim of this study was to assess the reliability of the sonographic Breast Imaging Reporting and Data System (BIRADS) classification in differentiating benign from malignant breast masses. Patients and Methods: This is prospective study involved 50 asymptomatic females their age range from 40 to 70 years. These females are carefully selected from a lot number of females who subjected to screening mammography. These 50 females with mammographically dense breast undergo additional screening by ultrasonography. To assess the role of ultrasound in screening of female with mamoghraphiclly dense breast at radiology department of Al- zahraa university hospital. The present study started at January 2019 till August 2019. Results: Lesions that are classified as BIRADS II all were benign and not subjected to histopathology, while lesions classified as BIRADS III, IV were subjected to histopathology. Among all lesion classified as BIRADS III 94.5% were benign and only 5.5% were malignant, finally lesions classified as BIRADS IV show 100 % malignant. Of the 21 lesion subjected to histopathology 17 were benign and 4 were malignant. Of the benign lesion all are fibro adenoma. Of the malignant lesion 3 lesions were invasive ductal carcinoma and one lesion was invasive lobular carcinoma. The results of the present study demonstrate the clear association between ACR BTIRADS classification and the pathology results. Conclusion: Every woman in the state of Connecticut who undergoes mammography and demonstrates breast density >50% must be informed of the following: ‘‘If your mammogram demonstrates that you have dense breast tissue, which could hide small abnormalities, you might benefit from supplementary screening tests, which can include abreast ultrasound screening or a breast MRI examination, or both, depending on your individual risk factors.

[Magda Shaaban Yakoot, Abdalla Hussein Ahmed, Gehan Hassan Gamal, Hanan Shawky Mohammed Al Sorady. The Role of Ultrasound in Screening of Dense Breast. N Y Sci J 2019;12(12):41-48]. ISSN 1554-0200 (print); ISSN 2375-723X (online). http://www.sciencepub.net/newyork. 6. doi:10.7537/marsnys121219.06.

 

Keywords: Ultrasound, Dense Breast

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Impact of serum uric acid level in patients with acute myocardial infarction

 

Tawfik N.M (1), Ahmad. F. Thabet (2), Ghada. Hassan (3), Mostafa Mahmoud Abd-Elaal (4).

 

1.  Professor of internal medicine Faculty of medicine–Assiut University

2.  Assistant Professor of internal medicine Faculty of medicine–Assiut University

3.  Lecturer of internal medicine Faculty of medicine–Assiut University

4.  Resident doctor at internal medicine Faculty of medicine–Assiut University

Department Of internal medicine, Faculty of Medicine, Assuit University

 

Abstract: Background: Acute myocardial infarction (AMI) continues to be a significant health problem and leading cause of death worldwide. increased serum uric acid level are observed in (AMI) patients and associated with high morbidity & mortality. Studies have shown that there is a close correlation between serum uric acid concentration and Killip classification for heart failure in patients of acute myocardial infarction: as uric acid levels are higher in patients with higher Killips class. Objectives: To assess the clinical value of serum uric acid level in early diagnosis & as a Prognostic value regarding complication and mortality during hospital stay. Material and methods: The study included 100 patients diagnosed as ( AMI ) besides 50 subjects as Control group. Serum uric acid level was measured on day 0, day 3 & day 7 of admission. Killip’s classification was carried out and correlated with serum uric acid level with estimation of complications and mortality during hospital stay. Results: levels of uric acid- in three samples- in day of admission, 3rd day and 7th day were significantly higher in patients with AMI in the three samples with mean ± SD (10.88 ± 2.45, 8.33 ± 2.01 and 7.37 ± 1.91 mg/dl respectively) in comparison to the control group in which mean ± SD were (6.13 ± 1.95, 5.11 ± 1.43 and 5.02 ± 1.23 mg/dl respectively), with P value of ( p< 0.02, p < 0.02 and p < 0.01) respectively. Patients with khillip class IV had the highest level of serum uric acid in comparison to other classes at (day 0), 3rd day and 7th day. Serum uric acid was significantly higher in those patients with complications than those without complications with P value was 0.04, 0.03 and 0.04 respectively. Also, Serum uric acid was significantly higher in 20 (20% ) died patients compared to 80 (80%) survived patients with P value was < 0.01, < 0.02 and < 0.01 respectively. Conclusion: Serum uric acid was significantly elevated in patients with myocardial infarction compared to controls, patients with high serum uric levels had higher khillip classes, complications and had higher mortality So serum uric acid can be used as a prognostic marker regarding complication and mortality in patients with acute myocardial infarction.

[Tawfik N. M, Ahmad. F. Thabet, Ghada. Hassan, Mostafa Mahmoud Abd-Elaal. Impact of serum uric acid level in patients with acute myocardial infarction. N Y Sci J 2019;12(12):49-53]. ISSN 1554-0200 (print); ISSN 2375-723X (online). http://www.sciencepub.net/newyork. 7. doi:10.7537/marsnys121219.07.

 

Keywords: uric acid, killip classification, myocardial infarction

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Discharge Heart Rate as a Predictor of Left Ventricular Adverse Remodeling in ST-Segment Elevation Myocardial Infarction in Patients Treated with Primary Percutaneous Coronary Intervention

 

Mohamed Mahmoud Ramadan Abdel Razek (M.B.B.Ch), Seham F. Badr MD, Hatem M. Elsokkary MD, Ayman A. Gaafar MD.

 

Cardiology Department, Faculty of Medicine, Tanta University.

 

Abstract: Background: Coronary artery disease is considered the most common cause of death around the world. Left ventricular (LV) dysfunction is the single strongest predictor of mortality and one of the most prevalent and deadly complications following ST-segment elevation myocardial infarction. Objectives: study the discharge heart rate in patients with acute ST-elevation myocardial infarction who were treated by primary PCI as a predictor of LV remodelling and dysfunction. Methods: study population were treated with primary percutaneous coronary intervention, DHR was calculated from predischarge 12-lead electrocardiography. LV volumes were measured with two-dimensional transthoracic echocardiography at baseline and 3-month follow-up. Variables independently associated with the occurrence of LV remodelling were investigated. Results: LV remodelling occurred in 36.6% of patients. Compared with patients without remodelling, these patients had higher DHR (76.0±6.1 bpm vs 70.1±7.8 bpm), hypertension (72.7% vs 21.0%), older age (61.3+12.6 vs 54.6+ 11.6), Diabetes mellitus (77.3% vs 42.0%), culprit LAD (77.3 % vs 50%), more than one vessel disease, higher discharge EF (32-52% vs 34-62%) and higher E/e’. The independent predictors were higher discharge heart rate, LAD as culprit vessel, HTN and discharge E/e’.

[Mohamed Mahmoud Ramadan Abdel Razek, Seham F. Badr, Hatem M. Elsokkary, Ayman A. Gaafar. Discharge Heart Rate as a Predictor of Left Ventricular Adverse Remodeling in ST-Segment Elevation Myocardial Infarction in Patients Treated with Primary Percutaneous Coronary Intervention. N Y Sci J 2019;12(12):54-61]. ISSN 1554-0200 (print); ISSN 2375-723X (online). http://www.sciencepub.net/newyork. 8. doi:10.7537/marsnys121219.08.

 

Keywords: Left ventricular remodelling – discharge heart rate– primary percutaneous coronary intervention – ST-segment elevation acute myocardial infarction.

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Cardiac Catheterization for Congenital Heart Disease, What are The Predictors of The Adverse Events, Single-Center Experience

 

Ahmed Essam Mabrouk*, Seham Fahmy Badr, Raghda Ghonimy El Sheikh, Ayman Ahmed Gaafar

 

Department of Cardiology, Faculty of Medicine, Tanta University

E-mail: ahmed.mabrouk@live.com

 

Abstract: Background: Over the last decade, the use of cardiac catheterization (CC) as a primary treatment modality in congenital heart disease has increased. With the expansion of cardiac catheterization for congenital heart disease (CHD) and its shift from being a diagnostic tool to a therapeutic one, adverse events related to CC have become a major concern to pediatric interventional cardiologists. Objective: This study determined the predictors of the different adverse events that occurred during diagnostic or interventional cardiac catheterization for patients with congenital heart diseases; their incidence and management at Tanta university hospital. Patients and Methods: Our study included 380 patients diagnosed with congenital heart disease and elected for either diagnostic or interventional cardiac catheterization in Tanta university hospital, cardiology department, from July 2016 to July 2018. Results: Incidence of overall adverse events (AE) was higher among interventional procedures (84.6%) than diagnostic procedures (15.38%). Risk factor analyses for the studied cases demonstrated that no variable showed significant difference in the occurrence of major adverse events. The variables that showed significant relation to the occurrences of overall adverse events were type of CHD (P 0.045), procedure time (P 0.03), fluoroscopy time (P 0.004) and volume of contrast use (P 0.032). Conclusion: From the current study, it was concluded that adverse event incidence of cardiac catheterization for congenital heart disease carried out at cardiology department of Tanta university hospital department is consistent with the incidence of several international renowned centers. Factors that showed significant relation to the occurrence of adverse events and can be considered predictors of adverse events were type of congenital heart disease, procedure and fluoroscopy time and volume of contrast use.

[Ahmed Essam Mabrouk, Seham Fahmy Badr, Raghda Ghonimy El Sheikh, Ayman Ahmed Gaafar. Cardiac Catheterization for Congenital Heart Disease, What are The Predictors of The Adverse Events, Single-Center Experience. N Y Sci J 2019;12(12):62-71]. ISSN 1554-0200 (print); ISSN 2375-723X (online). http://www.sciencepub.net/newyork. 9. doi:10.7537/marsnys121219.09.

 

Keywords: Cardiac Catheterization, Congenital Heart Disease, Predictors of The Adverse Events

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Admission Hyperglycemia as a Predictor of Adverse Outcome in Non-Diabetic STEMI Patients Treated by Primary Percutaneous Coronary Intervention

 

Marwa R. salama MSc, Ayman M. El saeed MD, Taymoor M. Abd Allah MD and Ahmed F. Abd El Gawad Elaarag MD.

 

Cardiology Department, Faculty of Medicine, Tanta University, Egypt.

 

Abstract: Background: Admission hyperglycemia is associated with high inhospital and long-term adverse events in patients that undergo primary percutaneous coronary intervention (PCI). Objectives: measure admission blood glucose level in non diabetic patients with acute ST-elevation myocardial infarction who were treated by primary PCI as a predictor of inhospital mortality. Methods: The patients were analyzed in subgroups categorized according to the groups of admission glucose measurements. Group I (glucose equal or less than 110 mg/dl) - Group II (glucose from 111 to 130 mg/dl) - Group III (glucose level above 131 mg/dl.). The study compared between those three groups in the acute stage during hospitalization of the patients according to TIMI Flow and Major Adverse cardiac event (MACE) (Cardiogenic shock - Periprocedural Death Ventricular arrhythmia – Re infarction- Contrast induced nephropathy Acute heart failure). Results: High admission blood glucose associated with more LV systolic dysfunction. In addition recurrent anginal attacks, arrhythmias and cardiogenic shock were also more frequent among those patients. Hyperglycemia can cause QT-interval prolongation, which can trigger ventricular arrhythmias in those with underlying coronary artery disease. also associated with increase risk for developing contrast induced nephropathy In Our study we found that Patients with elevated blood glucose level had high level of CKMB due to more necrosis of myocardium. Also had high risk for developing TIMI 0 or “no-reflow” and peri-procedural death - cardiogenic shock – ventricular arrhythmia- acute heart failure –re infarction – contrast induced nephropathy.

[Marwa R. salama, Ayman M. El saeed, Taymoor M. Abd Allah and Ahmed F. Abd El Gawad Elaarag. Admission Hyperglycemia as a Predictor of Adverse Outcome in Non-Diabetic STEMI Patients Treated by Primary Percutaneous Coronary Intervention. N Y Sci J 2019;12(12):72-79]. ISSN 1554-0200 (print); ISSN 2375-723X (online). http://www.sciencepub.net/newyork. 10. doi:10.7537/marsnys121219.10.

 

Keywords: hyperglycemia, ST-segment elevation myocardial infarction, mortality, major adverse cardiac events

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Assessment of Left ventricular function in patients with mitral valve incompetence before and after mitral replacement

 

Nourhan Hossam Elden Msc, Mohamed Elsaid Elseteiha MD, Mona Adel Elsaidy MD, Amany M. El Lithy MD.

 

Cardiology Department, Faculty of Medicine, Tanta University, Egypt

 

Abstract: Background: The mitral valve repair or replacement is indicated for patients with symptomatic mitral incompetence. When operative treatment is being considered, the chronic and often slowly but relentlessly progressive nature of MR must be weighed against the immediate risks and long-term uncertainties attendant on surgery, especially if mitral valve replacement (MVR) is required. Aim of study: study and assess the left ventricular function in patients with mitral valve incompetence before and after mitral replacement. Materials and Methods: This study included 25 patients with mitral valve incompetence before and after MVR followed up in the outpatient department, cardiology department, Tanta University or admitted to cardiology department from June 2018 to June 2019. Intervention: All patients underwent mitral valve replacement. Outcome Measurements and Statistical Analysis: Data were expressed as mean ± standard deviation, ranges or percentages. P value was considered significant if <0.05. The relation between LVEF preoperative to LVEF (3 and 6 months postoperative) was demonstrated using ANOVA test. Results: There was significant statistical difference with reduction of mean LVEF by Simpson method from 50.67 to 43.42 in comparison between preoperative and after 3 months with P value 0.001. Also, between preoperative and after 6 months measurement there was reduction of mean EF from 50.67 to 43.17 with P value 0.001. There was significant statistical difference in comparison of mean GLS between preoperative and after 3 months from -19.3 to -15.5 with P value 0.001. Also, between preoperative and after 6 months measurement there was reduction of mean GLS from -19.3 to -15.33 with P value0.001 Conclusions: In MR there is an increase in the volume overload of LV which keeps the EF in the normal range when contractility is already impaired. After replacement of the mitral valve this is reduction of the LVEF with the internal dimensions after relieving the overload. Using other echocardiographic parameters like pulmonary artery pressure, LA volume help in determining the time of intervention especially in asymptomatic patients.

[Nourhan Hossam Elden, Mohamed Elsaid Elseteiha, Mona Adel Elsaidy, Amany M. El Lithy. Assessment of Left ventricular function in patients with mitral valve incompetence before and after mitral replacement. N Y Sci J 2019;12(12):80-89]. ISSN 1554-0200 (print); ISSN 2375-723X (online). http://www.sciencepub.net/newyork. 11. doi:10.7537/marsnys121219.11.

 

Keywords: Assessment; Left ventricular; function; patient; mitral valve incompetence; mitral replacement

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Three Dimensional Transesophageal Echocardiography versus Conventional Two Dimensional Transesophageal Echocardiography in Evaluation of Suitability of Atrial Septal Defect for Transcatheter Closure

 

Reem Ayman Sayed Rashed, Sahar A. Elshedoudy, Hanan K. Kassem, Ehab A. Elgendy, Ibtsam K. Ibrahim, Fatma A. Taha.

 

Cardiovascular Department, Faculty of Medicine, Tanta University, Egypt

 

Abstract: Background: Atrial septal defect (ASD) is the most common acyanotic congenital cardiac defect, occurring in 0.1% of births. Transcatheter closure of ASD Secundum type is the preferred tool as long as the defect is amenable for closure. Three-dimensional (3D) transesophageal echocardiographic (TEE) imaging is used in ASD closures. 3D TEE imaging obviates the need for mental reconstruction of 3D structures from two-dimensional images. Objectives: The study was to evaluate the feasibility of 3D TEE versus two-dimensional (2D) TEE to select the patient’s candidate for percutaneous closure and to guide the procedure up to the device deployment. Methods: This study was conducted on a number of thirty patients diagnosed with ASD secondum. Two dimensional TEE and Real time (RT) three dimensional TEE were done to confirm the suitability of ASD for transcatheter closure and repeated alternatively in the catheterization Laboratory before and during guiding the procedure. ASD size, site, rims, associated patent foramen ovale (PFO) and aneurysmal tissue and number of fenestrations within the associated aneurysm were compared by both tools. Results: by comparing the data obtained by 2D and 3D TEE, there was no significant difference between both as regard size and site of ASD, detection of associated PFO and aneurysm while 3D TEE was more superior in assessing the number of fenestrations within aneurysmal ASD. Both tools were nearly the same assessing the sufficiency of Aortic, Atrioventricular, posterosuperior rims while 3D TEE was more superior assessing the sufficiency of posteroinferior and posterior rims. Conclusion: RT 3D TEE as an adjunct to 2D TEE is a feasible and safe tool to guide transcatheter device closure of interatrial septal defects especially in challenging cases with complex ASD morphology. 3D TEE was further superior in assessing the fenestrations and posterior and posteroinferior rims.

[Reem Ayman Sayed Rashed, Sahar A. Elshedoudy, Hanan K. Kassem, Ehab A. Elgendy, Ibtsam K. Ibrahim, Fatma A. Taha. Three Dimensional Transesophageal Echocardiography versus Conventional Two Dimensional Transesophageal Echocardiography in Evaluation of Suitability of Atrial Septal Defect for Transcatheter Closure. N Y Sci J 2019;12(12):90-94]. ISSN 1554-0200 (print); ISSN 2375-723X (online). http://www.sciencepub.net/newyork. 12. doi:10.7537/marsnys121219.12.

 

Key words: Atrial septal defect, Real time three dimensional transesophageal echocardiography, transcatheter closure

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The manuscripts in this issue were presented as online first for peer-review, starting from November 28, 2019. 

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