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Effects of Momordica charantia on the serum chemistry and some reproductive parameters in  the Female Wistar Rats.

Oyeyemi Matthew O, Esan Oluwaseun, O, Esan Olasunmbo O, Oyerinde Caleb M, Uwalaka Emmanuel C

Department of Veterinary Surgery and Reproduction, University of Ibadan

Department of Veterinary Medicine, University of Ibadan, Department of Veterinary Microbiology and Parasitology, University of Ibadan

 oiuseunsol@yahoo.co.uk

Abstract:

Momordica charantia (Bitter melon) has been used in African and Asian herbal medicine for a long time. This work is however designed to investigate the effect of Momordica charantia leaf extract on the reproductive parameters of the female Wistar Rats.  The fifteen female wistar rats  used in this study were divided into 3 groups of five rats each. The rats in groups A and B were treated with a daily dose of 300mg and 600mg per-os of the leaf extract for seven (7) days respectively while control group C received distilled water. There was a significant difference (P≤0.05) between the mean packed cell volume, White blood cell Values, Mean corpuscular volume, Mean heamatocrit concentration and Mean corpuscular heamatocrit concentration of the different groups. There was a significant difference (P≤0.05) in the valves of Protein, Albumin, Globulin, Sodium, Blood urea nitrogen and AST between the groups. The reproductive indices, showed a significant difference (P≤0.05) in the mean value of the length of the uterine horn and diameter of the right ovary whereas; there is no significant difference (P≥0.05) in the mean length values for the other parts of the reproductive tract across the groups. There was a significant difference (P≤0.05) in the mean values of the weight of the left ovary across the groups but between the groups in the right ovary. However, there was no significant difference (P≥0.05) in the mean values of the weight of the left and right kidneys, spleen and the weight of reproductive tract. It is concluded that the leaf extract of Momordica charantia probably induce follicular growth which may be responsible for the heavier ovaries in the test groups.

[Oyeyemi Matthew O, Esan Oluwaseun, O, Esan Olasunmbo O, Oyerinde Caleb M, Uwalaka Emmanuel C. Effects of Momordica charantia on the serum chemistry and some reproductive parameters in  the Female Wistar     Rats. Nat Sci 2022, 20(10):1-5].ISSN1545-0740(print); ISSN2375-7167(online). http://www.sciencepub.net/nature

01. doi:10.7537/marsnsj201022.01.

Key Words: Momordica charantia, Female Wistar Rat, Reproductive parameters, Serum Chemisty, Ovary.

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Flood Forecasting By Monitoring Rainfall Intensity And Cloud Movement (on the example of the Fergana Valley)

Makulov Jasurbek Taxirjonovich

Teacher at Namangan State University

Corresponding Author: Dr. Jasurbek Takhirjanovich, Namangan State University, Namangan, Uzbekistan

Abstract: In the article Areas of flooding caused by torrential rains in the republic. Rain intensity An analysis of flood targeting technologies in the regions was carried out.

[Makulov Jasurbek Taxirjonovich. Flood Forecasting By Monitoring Rainfall Intensity And Cloud Movement (on the example of the Fergana Valley). Nat Sci 2022, 20(10):6-10].ISSN1545-0740(print);ISSN2375-7167(online). http://www.sciencepub.net/nature   02.doi:10.7537/marsnsj201022.02.

Keywords: emergency, danger, threat, monitoring, forecasting, targeted alerts, rain intensity, information exchange.

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Four-year retrospective survey of water, sanitation and hygiene associated diseases in Onitsha, Nigeria

(2011-2014)

Michael Uchenna Orji¹, Ikechukwu Okoli*¹, and Emmanuel Emeka Ezenwaji²

¹Department of Applied Microbiology, Nnamdi Azikiwe University, P.M.B. 5025, Awka.

²Department of Geology, Nnamdi Azikiwe University, P.M.B. 5025, Awka.

*Corresponding Author

E-mail: ik.okoli@unizik.edu.ng

Phone: +234-706-117-4822

ABSTRACT

Objective: Ex-post-facto to research design was used to assess the occurrence of dysentery, diarrhea, typhoid and malaria in Onitsha, Nigeria within the period 2011-2014 using records available at four hospitals strategically located within the city.  Methods: Responses from questionnaires and visual observations during on-the-spot check for practices of open defecation sources of water supply and waste disposal system in the city were used to substantiate information from the hospital records. Results: Occurrences of the four diseases were very high in the city.  Malaria had the highest occurrence (16,393 in 2011, 14,974 in 2012, 12,720 in 2013 and 12,193 in 2014).  Typhoid fever had occurrence of 6,459 in 2011, 4,865 in 2012, 5,010 in 2013 and 5,061 in 2014.  Diarrheal diseases recorded 5,194 in 2011 while dysentery occurrence was 1,143 in 2011, 1488 in 2012, 1,011 in 2013 and 1,123 in 2014.  The occurrence of the four diseases in the area was found not to be dependent on season.  Diarrhea was found to occur more among age group 0-4 years. Malaria showed slightly higher occurrence in females than males. Conclusion: There were evidence of bad environmental hygiene and sanitation practices in the city and these were thought to be responsible for the high prevalence of the diseases in the area.

[Michael Uchenna Orji, Ikechukwu Okoli, and Emmanuel Emeka Ezenwaji. Four-year retrospective survey of water, sanitation and hygiene associated diseases in Onitsha, Nigeria (2011-2014). Nat Sci 2022, 20(10):11-16]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature   03. doi:10.7537/marsnsj201022.03.

Keywords:    water, sanitation, hygiene, diseases.

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The use of agile enterprise architecture in the development of enterprise architecture

Elias yavari

Department of computer engineering, software trends, martyr Beheshti University, Tehran, Iran

Abstract

With the emergence of new areas of IT and business change is an integral part of their survival and success are far more serious problems faced. Changes in the needs of users who seek changes in the business environment requires organizations to the fluctuations requires not only flexible approach, but in order to grow their own benefit. To achieve this it will not be possible unless the enterprise architecture. With respect to the challenges and risks of the enterprise architecture, agile development in this paper based on the study of the subject that can-be enterprise architecture concepts used to develop agility? And the development of an agile enterprise architecture can be achieved qualitative characteristics of enterprise architecture?

[Elias yavari. The use of agile enterprise architecture in the development of enterprise architecture. Nat Sci 2022,20(10):17-21]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature   04. doi:10.7537/marsnsj201022.04.

Keywords: architecture, agile development, enterprise architecture, agile, quality properties

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The association of Adiponectin Gene Polymorphisms (-11391G/A), (+45T/G) with WC and Type 2 Diabetes in North East India

Majid Khandouzi^1*, Manab Deka², Morteza Kordafshari³, Priyanka Kashyap⁴, Namrata Kumari⁵

¹PhD Scholar, Medical Biotechnology, Dept of Bioengineering and Technology, Gauhati

University, Guwahati, Assam, India.  Ph: +918011588140, E-mail: majid.khandozi@gmail.com .

² Postdoc  Microbiology & Biomedical Sciences, Proffesor & Head, Dept of Bioengineering and Technology, Gauhati University, Guwahati, Assam, India.

³ PhD Scholar, Medical Biotechnology, Dept of Bioengineering and Technology, Guahati University, Guwahati, Assam, India.

⁴ Phd Scholar, Dept of Bioengineering and Technology, Gauhati University, Guwahati, Assam, India.

⁵ Phd Scholar, Dept of Bioengineering and Technology, Gauhati University, Guwahati, Assam , India.

Abstract: Background: Adiponectin is a protein, secreted from adipose tissue, according to numerous studies that have been done before, its plasma levels are associated with different parameters  of metabolic syndrome. It seems that this effect results from the interaction of genetic (polymorphisms in the adiponectin gene) and environmental factors (obesity). The present study aimed to investigated the possible association between two SNPs of adiponectin gene at position (+ 45T/G) and (-11391G/A) with increased of waist circumference (WC) and type 2 diabetes mellitus patients in North East, Guwahati, India. Method: This study is a case - control study with 121 diabetic patients were selected as cases group and 87 healthy people selected as controls group. After extraction of DNA, genotyping was performed by PCR-RFLP method. Results: We don’t observed  a significant association between adiponectin gene polymorphism (+45T/G) and waist circumference(WC). In diabetic patients over 40 years old we observed a significant association between adiponectin gene polymorphism (-11391 G/A) and waist circumference(WC) (P = 0.021). Conclusion: It seems that the role of adiponectin  polymorphism (+45 T / G) in the creation of type 2 diabetes independent to abdominal obesity and adiponectin polymorphisms of ( -11391G / A)  in type 2 diabetes depend to abdominal obesity in people older than 40 years (waist circumference  <90).

[Majid Khandouzi, Manab Deka, Morteza Kordafshari, Priyanka Kashyap, Namrata Kumari. The association of Adiponectin Gene Polymorphisms (-11391G/A), (+45T/G) with WC and Type 2 Diabetes in North East India. Nat Sci 2022,20(10):22-27]. ISSN 1545-0740 (print); ISSN 2375-7167(online). http://www.sciencepub.net/nature   05. doi:10.7537/marsnsj201022.05.

Keywords: Adiponectin, Polymorphisms, Type2 diabetes, WC, Abdominal obesity.

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 Evaluation of Okra Production among Smallholder Farmers in Kabba-Bunu Area of Kogi State, Nigeria

Babalola, T.S., Ibitoye-Ayeni, N.K., Alemoru, M.O., Ayodele, F.G. and Lawal, J.A.

Kabba College of Agriculture, Division of Agricultural Colleges, Ahmadu Bello University

P.     M.B 205, Kabba. pauloxti@yahoo.com

Abstract

The study was conducted to identify factors of Okra production in Kabba/Bunu Local Government Area. 60 Okra farmers were identified and given a well structure questionnaire. 55 questionnaires were returned by the respondents. The questionnaire were collected and organized for analysis. Percentage was used to analyze the data collected. Results from the study shows that majority of the farmers are male, within the age of 47-56 and above, main occupation is farming; 18.18% are civil servants. Education level is low; 32.73% had no formal education while 29.10% had primary education. Factors affecting Okra production in the area include land acquisition, size of farm land, land preparation method and source of capital. For management practices the study revealed that there is low use of fertilizer (23.64%) and herbicide (25.45%) among farmers, also majority of the farmers use local variety (54.55%). The study established need for improvement in management practices for Okra production in the study area.

[Babalola, T.S., Ibitoye-Ayeni, N.K., Alemoru, M.O., Ayodele, F.G. and Lawal, J.A.. Evaluation of Okra Production among Smallholder Farmers in Kabba-Bunu Area of Kogi State, Nigeria. Nat Sci 2022,20(10):28-33]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature  06. doi:10.7537/marsnsj201022.06.

Key words: Management, Okra, Production, Farmers, Factors

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Effect of inorganic and organic selenium on performance of dairy Zaraibi goats and their suckling kids

Mostafa Mohamed El-Nahrawy¹, Mahmoud El-Sayed El-Gendy¹, Kotb Fath Elbab El-Riedy¹, Mohsen Abd El-Aziz Zommara² and Mohamed Abed Ghanimah²

¹ Animal Production Research Institute, Agricultural Research Center, Dokki, Giza, Egypt.

² Department of Dairy Science, Fac. of Agric., Kafrelsheikh Univ., Kafr El-Sheikh, 33516, Egypt.

ABSTRACT

Thirty Zaraibi goats with average body weight of 42.45±1.25 kg and aged 3-5 years after kidding were divided into three similar groups (10 in each). All goats were fed the basal diet consisted of 50% concentrate (concentrate feed mixture + barley grains) and 50% roughage (fresh berseem + wheat straw). The goats in the first group (control) were fed the basal diet without supplement (G1). The other two groups were supplemented with 0.3 mg Se/kg DM intake as inorganic selenium (sodium selenite) in G2 or organic selenium (selenium yeast) in G3, respectively. Results showed that nutrients digestibility coefficients of DM, OM, CP, CF, EE and NFE as well as feeding values of TDN and DCP were significantly (P≤0.05) higher for G3 compared to G1 with insignificant differences with G2.No significant differences in average daily intake of DMI and CPI among different groups. Meanwhile, the average daily intake of TDN and DCP were greater (P≤0.05) for G3 compared to G1 with insignificant (P≤0.05) differences with G2.Group 3 showed significantly (P≤0.05) the highest yield of actual milk and 4% fat corrected milk (FCM) followed by G2, while G1 had the lowest yield. The contents of fat, solids not fat (SNF) and total solids (TS) were significantly (P≤0.05) higher in G3 compared to G1 with insignificant differences with G2. The highest yield of all milk constituents (fat, protein, lactose, SNF, TS and ash) were detected significantly (P≤0.05) in G3 followed by G2, while the lowest values were in G1. Group 1 recorded significantly (P≤0.05) the highest amounts of DM, TDN, CP and DCP per kg 4% FCM followed by G2, while the lowest values were in G3.Average daily feed cost was nearly similar for different groups, while feed cost per 1 kg 4% FCM was the highest in G1 followed by G2, but G3 had the lowest cost. Group 3 recorded significantly (P≤0.05) the highest output of daily 4% FCM yield, net revenue and economic efficiency followed by G2, however G1 had the lowest values. Number of weaned kids was higher and mortality rate was lower in G3 followed by G2, but G1 had the opposite trend (P≤0.05).Weaning weight (WW), total weight gain (TWG) and average daily gain (ADG) increased significantly (P≤0.05) in G3 compared to control G1, with insignificant differences with G2.Suckled milk as g per kid per day and the cost of suckled milk increased, while suckled milk as kg per kg weight gain decreased with selenium additives without significant differences. Output of ADG, net revenue and economic efficiency expressed as the percentage of net revenue compared to cost of suckled milk increased significantly (P≤0.05) with inorganic and organic selenium additives in G2 and G3 compared to control G1.

[Mostafa Mohamed El-Nahrawy, Mahmoud El-Sayed El-Gendy, Kotb Fath Elbab El-Riedy, Mohsen Abd El-Aziz Zommara and Mohamed Abed Ghanimah. Effect of inorganic and organic selenium on performance of dairy Zaraibi goats and their suckling kids. Nat Sci 2022,20(10):34-44]. ISSN 1545-0740(print); ISSN 2375-7167(online).http://www.sciencepub.net/nature  07. doi:10.7537/marsnsj201022.07.

Keywords: Zaraibi goats, inorganic and organic selenium, digestibility, intake, milk yield and composition, economic efficiency, kids growth

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COMPREHENSIVE ASSESSMENT OF THE DELTA'S NATURAL CONDITIONS AND RESOURCES FOR THE IMPLEMENTATION OF COMPLEX DIFFERENTIATED MEASURES IN THE DESERTIFIED PART OF THE AMUDARYA DELTA

Professor Vaxab Asamovich Rafikov, Ziyodulla Akramovich Ganiyev, Elyor Aliyevich Fayziyev

ABSTRACT. This article provides a detailed scientific analysis of the natural conditions of the desert part of the Amudarya delta, rational use of resources, tugai ecosystems, ecological condition of irrigated lands and phytomeliorative and hydro-ameliorative conditions in the region, describes the proposals and recommendations for the future design of hydraulic structures. The importance of using the natural resources of the region in the development of the economy and focusing on optimizing the environmental situation is highlighted, and scientific conclusions are made on ensuring environmental sustainability.

[Vaxab Asamovich Rafikov. COMPREHENSIVE ASSESSMENT OF THE DELTA'S NATURAL CONDITIONS AND RESOURCES FOR THE IMPLEMENTATION OF COMPLEX DIFFERENTIATED MEASURES IN THE DESERTIFIED PART OF THE AMUDARYA DELTA. Nat Sci 2022,20(10):45-50]. ISSN 1545-0740(print); ISSN 2375-7167(online). http://www.sciencepub.net/nature  08. doi:10.7537/marsnsj201022.08.

KEYWORDS: differential, assesment, hydraulic structures, universal, landscape, complexity principle, geosystem, genetic principle, dynamics, natural environment, delta, transformation, morphological, eluvial, hydromorphic, automorphic, intensive.

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Problems Of Classification And Grouping Of Geographical Places Names

Abbasov Subkhon Burkhonovich, Valiyeva Shakhnoza Islomovna

Department of Geography and Ecology, Samarkand State University named after Sharof Rashidov, 140104, Samarkand, Uzbekistan

Telephone: +998937298973 e-mail: shaxnoza-valieva82@mail.ru

Abstract: The article provides information on toponymic classifications of geographical objects. The toponymic classification of natural and man-made geographical objects is covered. Classifications of geographers, toponymist scientists are analyzed.

[Abbasov Subkhon Burkhonovich, Valiyeva Shakhnoza Islomovna. Problems Of Classification And Grouping Of Geographical Places Names. Nat Sci 2022,20(10):51-54]. ISSN 1545-0740 (print); ISSN 2375-7167(online).         http://www.sciencepub.net/nature  09.doi:10.7537/marsnsj201022.09.

Keywords: toponym, classification, toponymic denotations, hydronym, oykonim, oronim

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Efficacy of Rejuvenation of Human Gut microbiome for Covid and Chronic Illnesses

By Aditi Irabattin

Abstract

When the world was stricken by Covid-19 there was no known cure to this disease due to its unexplored nature, a lot of trial-and-error methods were used for not curing this disease but keeping the numbers substantial. Drugs like remdesivir, hydrochloroquinine and more exploratory drugs were initially used to keep the disease under control, soon all of that failed and then the urge for vaccine production grew at an alarming rate Serum institute, Pfizer were only of the first few companies to launch their products. Two shots of vaccines terms for a fully vaccinated person who is immune to the virus but the mutation is how the virus lives, it mutates in order to live, every time the virus mutates it changes its chemical and as the structure the effect that it has on the human body is different and administering vaccine every time is not exactly feasible and the biological impact that it would have on the human body is beyond imagination, thus a nature cure is of utmost importance. This paper elucidates the importance of prebiotics and the beneficial, long-term impact that it has on the body. The human body has inbuilt wonderful mechanism called self -defence or self- healing mechanism which can set itself right  without need of medication,  provided  it  is  given  a  chance  to  heal itself as per Nature Cure principles. Food has very important role in natural healing specially eradication of toxic elements regularly. It has been evident that Nature Cure has great emphasis on "Food as Medicine" in not only for healing but maintenance of vital energy levels seamlessly. This paper takes a holistic approach towards looking at this problem instead of a reductionist approach, instead of focusing on one approach to cure, it looks from multiple perspective like nature cure, medications, and lastly vaccines.

[By Aditi Irabattin. Efficacy of Rejuvenation of Human Gut microbiome for Covid and Chronic Illnesses. Nat Sci 2022, 20(10):55-76].ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature

10.doi:10.7537/marsnsj201022.10.

Keywords： Efficacy; Rejuvenation; Human; Gut; microbiome; Covid; Chronic Illnesses

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