Science Journal

 

 

Cancer Biology

 

ISSN: 2150-1041 (print); ISSN: 2150-105X (online), doi prefix:10.7537, Quarterly

 
Volume 13 / Issue 4, Cumulated No. 52, December 25, 2023
Cover (jpg), Cover (pdf), Introduction, Contents, cbj1304

 

The following manuscripts are presented as online first for peer-review, starting from December 2, 2023

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CONTENTS  

No.

Titles / Authors /Abstracts

Full Text

No.

1

awareness AND perception towards the utilization of cervical cancer screening (CCS) SERVICES among nurses in A TEACHING Hospital in Ibadan, Nigeria

 

Akinpelu A.O1

1 Department of Health and Information Management Lead City University Ibadan, Nigeria

Agboola O.A 2

2 Department of Microbiology Lead City University Ibadan, Nigeria

Umezurike E.T 2*

2 Department of Microbiology Lead City University Ibadan, Nigeria

* Contact of Corresponding Author-

No. 1 Otudeko Drive Toll Gate Area Ibadan Oyo State

+2348135939991

umezurikee@yahoo.com

 

ABSTRACT: Invasive cervical cancer is the second-most common cancer in women world-wide, 80% of these cases were discovered through records to be from developing countries Although it can be readily detected in the premalignant phase, cervical cancer remains the second most common cancer in Nigeria and fifth in the United Kingdom. The objective of this study is to determine awareness and perception affecting utilization of cervical cancer screening services awareness, perception and factors affecting utilization of cervical cancer screening services among nurses in Adeoyo Maternity Teaching Hospital, Ibadan, Oyo State, Nigeria. The research was a descriptive and cross-sectional study conducted in Adeoyo Maternity Teaching Hospital Ibadan, Nigeria. The study showed a high level of perception 106 (59.9%) among the nurses within this study and the  nurses that had positive perception only 8 (19.0%) had undergone cervical cancer screening in the past. Their knowledge of cervical cancer was not poor; 97.7% of the respondents have heard of cervical cancer screening as a form of cervical cancer prevention and 168 (94.9%) are familiar with the age range (between 16-65 years old) that are eligible to go for CCS, only 128 (72.3%) were aware of modern day CCS equipment under Oyo state hospital management board facilities. However only 16 (9.0%) have worked in CCS unit and only 8 (4.5%) had privileged to attend refresher course training to enhance their knowledge of CCS practice. The findings of this study show that majority of the Nurses at Adeoyo Maternity Teaching Hospital though they are aware yet only few have undergone cervical cancer screening.

[kinpelu A. O. Agboola O.A. Umezurike E.T. awareness AND perception towards the utilization of cervical cancer screening (CCS) SERVICES among nurses in A TEACHING Hospital in Ibadan, Nigeria.Cancer Biology 2023;13(4):1-5]. ISSN: 2150-1041 (print); ISSN: 2150-105X (online). http://www.cancerbio.net  01.doi:10.7537/marscbj130423.01.

 

KEYWORDS: Nurses, Cervical Cancer, Screening, Awareness, Perception

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2

Research Literatures of Cancer Prevention

 

Dr. Mark Herbert

 

World Development Institute

39-06 Main Street, Flushing, Queens, New York 11354, USA, ma708090@gmail.com

 

Abstract: Cancer is the general name for a group of more than 100 diseases. Although there are many kinds of cancer, all cancers start because abnormal cells grow out of control. Untreated cancers can cause serious illness and death. The body is made up of trillions of living cells. Normal body cells grow, divide, and die in an orderly fashion. During the early years of a person’s life, normal cells divide faster to allow the person to grow. After the person becomes an adult, most cells divide only to replace worn-out or dying cells or to repair injuries. This article introduces recent research reports as references in the related studies.

[Dr. Mark Herbert. Research Literatures of Cancer Prevention. Cancer Biology 2023;13(4):6-31]. ISSN: 2150-1041 (print); ISSN: 2150-105X (online). http://www.cancerbio.net  02.doi:10.7537/marscbj130423.02.

 

Key words: cancer; life; research; literature; cell

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3

Research Literatures of New Ideas in Cancer Treatment

 

Dr. Mark Herbert

 

World Development Institute

39-06 Main Street, Flushing, Queens, New York 11354, USA, ma708090@gmail.com

 

Abstract: Cancer is the general name for a group of more than 100 diseases. Although there are many kinds of cancer, all cancers start because abnormal cells grow out of control. Untreated cancers can cause serious illness and death. The body is made up of trillions of living cells. Normal body cells grow, divide, and die in an orderly fashion. During the early years of a person’s life, normal cells divide faster to allow the person to grow. After the person becomes an adult, most cells divide only to replace worn-out or dying cells or to repair injuries. This article introduces recent research reports as references in the related studies.

[Dr. Mark Herbert. Research Literatures of Cancer Prevention.Cancer Biology 2023;13(4):32-85]. ISSN: 2150-1041 (print); ISSN: 2150-105X (online). http://www.cancerbio.net  03.doi:10.7537/marscbj130423.03.

 

Key words: cancer; life; research; literature; cell

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4

Clinicopathological Features of Non Hodgkin’s Lymphoma Patients Treated in Kasr Al-Ainy Centre of Clinical Oncology (Nemrock) from       2015 to 2020

 

Wedad B. Hashem, MD, Rasha Salama MD, Hadir Habib, Msc, Hamdy Zawam MD

 

Department of Clinical Oncology, Kasr Al-Ainy School of medicine, Cairo University, Egypt

E-mail: weedo_82@hotmail.com

 

Abstract: Background: Worldwide, non-Hodgkin lymphoma (NHL) is the most prevalent hematologic cancer. It has more than 40 major subtypes. The primary objective of this study is to evaluate the prevalence and clinicopathological features of different types of NHL and to study the impact of number of cycles of Rituximab on progression free survival of DLBCL patients. Our main secondary objective is to assess the incidence of CNS relapse in DLBCL.

Methods: This is a five-year retrospective (from January 2015 till January 2020) study of clinic-pathological features of NHL patients in Kasr Aini Clinical Oncology department, Cairo University. Final analysis of DLBCL patients data was done.

Results: During the period from January 2015 to January 2020 data of   lymphoid malignancies retrieved were 719 cases. Meanwhile among NHL, the diffuse large B cell lymphoma (DLBCL) was the commonest subtype forming 43% (251 patients). Only 186 patients of DLBCL were eligible for the final analysis. In our cohort, the median age at diagnosis was 50 years. We have found that patients with intermediate or high CNS-IPI were more likely to develop CNS relapse with a trend toward statistical significance (p= 0.08). Complete remission (CR) also increased to 60.1% of the patients after adding rituximab to CHOP. Median PFS for patients who achieved CR after first line of treatment was 13.5 months, while those who failed to achieve a response had a median PFS of 5 months, with p value <0.0001. Overall survival was significantly affected by the response after 1st line of chemotherapy; with the median OS for those who achieved favorable response was 20.8 versus 8.1 months for those who achieved no response after completion of the first line of chemotherapy.

Conclusion: The most prevalent lymphoma subtype in our study, accounting for 43% of the patients, was DLBCL. When added to chemotherapy, rituximab improved both CR and ORR. Furthermore, Rituximab plus chemotherapy had a noticeably longer overall survival.

Regarding CNS relapse and the impact of CNS IPI, we noticed that patients with intermediate or high CNS-IPI were at a higher risk of experiencing CNS relapse.

[Wedad B. Hashem, Rasha Salama, Hadir Habib, Hamdy Zawam. Clinicopathological Features of Non Hodgkin’s Lymphoma Patients Treated in Kasr Al-Ainy Centre of Clinical Oncology (Nemrock) from       2015 to 2020. Cancer Biology 2023;13(4):86-93]. ISSN: 2150-1041 (print); ISSN: 2150-105X (online). http://www.cancerbio.net  04.doi:10.7537/marscbj130423.04.

 

Keyword: DLBCL, Rituximab, CNS prophylaxis

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The manuscripts in this issue were presented as online first for peer-review starting from December 2, 2023

 All comments are welcome: editor@sciencepub.net

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doi prefix: 10.7537

Global Impact Factor: 0.324 (2012); 0.432 (2013); 0.543 (2014); 0.654 (2015)

InfoBase Index IBI Factor: 4.9 (2015); IF A2016: 3.29

InfoBase Index IBI Impact Factor (IF, 2019): 2.5

Journal Index I2OR

 

 

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